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The phase contrast microscope is widely used for examining such specimens as biological tissues. Phase contrast is a method used in microscopy and developed in the early 20th century by Frits Zernike. Zernike discovered that if you speed up the direct light path, you can cause destructive interference patterns in the viewed image. These patterns make details in the image appear darker against a light background.

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Nuclear Transplant Microscopes is a company devoted to providing microscopes needed for doing micromanipulation of cellular and genetic material within individual biological cells. We provide high quality micromanipulators capable of cell manipulation such as extracting, injecting, and transplanting cellular genetic nuclear material.